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Evidence Based Medicine


A well-built clinical question follows the PICO format.

P = Patient/Population: Describe the most important characteristics of the patient or population

I = Intervention: Describe the intervention (e.g. drug or treatment, diagnostic test, etc.)

C = Comparison: Describe the main alternative being considered (e.g. placebo, the gold standard, etc.)

O = Outcome: Describe what you're trying to measure, accomplish, improve, or affect

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